beat365在線體育官網

        College of Biological Science and Engineering

        黃達

        發布日期:2024-11-13 發布者:

        姓名:黃達

        性別:


        職稱:副教授

        學歷:博士

        QQ122636859

        電子郵件:huangda@fzu.edu.cn

        研究方向:生物醫用材料

        招生專業(方向):生物醫學工程(學碩)、生物工程(學碩)、生物技術與工程(專碩)

        教育工作經歷:

        2017.08-至今 beat365在線體育官網beat365在線體育官網,講師/副教授,碩士生導師

        2020.02-2022.07 美國弗吉尼亞聯邦大學/密蘇里科技大學,博士后

        2014.09-2017.07 中國科學院化學研究所,高分子化學與物理,博士

        2011.09-2014.07 中國科學院化學研究所,材料工程,碩士

        2007.09-2011.07 北京化工大學,高分子材料與工程,本科

        教學簡介:

        本科生課程:《藥物化學與藥物分析》、《藥劑學》、《生物高分子與膠體》、《生物醫學納米技術》

        研究生課程:《納米生物技術》、《藥物遞送系統》、《高分子與膠體化學》、《天然活性分子的功能與健康》

        科研簡介:

        主要從事生物醫用材料的設計制備及應用研究,包括(1)納米藥物遞送系統的構建及其在炎癥性疾病治療方面的應用;(2)醫用水凝膠的制備及其在抗感染傷口敷料、軟骨修復等方面的應用;(3)可降解醫用支架的制備及其在骨修復領域的應用;(4)檢測疾病標志物的生物傳感器的開發及應用。目前已在Angewandte ChemieAdvanced Science、Biomaterials、Advanced Healthcare Materials、Carbohydrate Polymers、Biosensors & Bioelectronics等本領域知名國際期刊上發表SCI論文40余篇,其中第一作者和通訊作者論文20余篇,授權發明專利4項。

        社會兼職:

        1)2022.06至今,擔任Frontiers in Bioengineering and Biotechnology: Biomaterials期刊審稿編輯

        2)擔任Carbohydrate PolymersInternational Journal of PharmaceuticsMaterials Today BioInternational Journal of Biological MacromoleculesFood Chemistry、Biomaterials ScienceJournal of Materials Chemistry B等國際學術期刊審稿人

        3)福建省福州市/莆田市科技特派員。

        科研項目:

        1)福建省自然科學基金面上項目,兼具活性氧清除和多藥遞送功能的羥乙基淀粉-姜黃素微粒的制備及其用于炎癥性腸病治療的研究,2023-2026,主持

        2)福建省自然科學基金青年項目,酸響應多級釋放納米載體用于抗癌藥物傳輸的研究,2019-2022,主持

        3)福建省教育廳中青年教師項目,姜黃素-茶多酚納米藥物的制備及應用,2018-2020,主持

        4)beat365在線體育官網科研啟動經費,利用茶多酚制備疏水藥物的新型納米制劑的研究,2017-2020,主持

        5)技術服務項目,透明質酸水凝膠的制備和表征,2024-2026,主持

        6)技術開發項目,基于體表腫瘤、慢性創面與脂肪組織工程等整形外科亞專業的臨床與基礎研究,2023-2026,主持

        7)技術開發項目,納米均孔膜的均相電化學發光傳感器的技術開發,2023-2025,主持

        8)技術開發項目,氫氣飽和生理鹽水納米鉑的制備及應用,2020-2022,主持

        9)國家自然科學基金面上項目,高穩定性新型全無機無鉛鈣鈦礦納米材料的合成及應用,2023-2026,參與(第二)

        10)建省科技廳合作項目,基于金納米團簇/二氧化鈦光催化材料的制備及其創面抗菌作用的研究,2022-2025,參與(第二)

        代表性論文:(*為通訊作者)

        1. Zhichao Yu, Zhenjin Xu, Ruijin Zeng, Man Xu, Haisu Zheng, Da Huang,* Zuquan Weng* and Dianping Tang.* D-band center engineered Pt-based nanozyme for personalized pharmacovigilance. Angewandte Chemie International Edition 2024, e202414625. IF=16.1

        2. Da Huang, Pedro Norat, Lin Qi, Anna Chernatynskaya, James D. Cole, Vimalin Jeyalatha Mani, Lei Xu, Xiaorong Liu,* and Hu Yang.* Consistent intraocular pressure reduction by solid drug nanoparticles in fixed combinations for glaucoma therapy. Advanced Science 2024, 2401648. IF=14.3

        3. Da Huang, Yongming Wang, Chenlan Xu, Minglang Zou, Yangcan Ming, Fang Luo, Zhenjin Xu, Ying Miao, Na Wang,* Zhenyu Lin, Zuquan Weng.* Colon-targeted hydroxyethyl starch-curcumin microspheres with high loading capacity ameliorate ulcerative colitis via alleviating oxidative stress, regulating inflammation, and modulating gut microbiota. International Journal of Biological Macromolecules 2024, 266, 131107. IF=8.4

        4. Da Huang, Jiahao Du, Fang Luo, Gang He, Minglang Zou, Yongming Wang, Zhenyu Lin,* Decheng Wu,* and Zuquan Weng.* Injectable hydrogels with integrated pH probes and ultrasound-responsive microcapsules as smart wound dressings for visual monitoring and on-demand treatment of chronic wounds. Advanced Healthcare Materials 2024, 2303379. IF=10

        5. Da Huang, Minglang Zou, Chenlan Xu, Yongming Wang, Zhenjin Xu, Wancong Zhang,* Shijie Tang,* and Zuquan Weng.* Colon-targeted oral delivery of hydroxyethyl starch-curcumin microcapsules loaded with multiple drugs alleviate DSS-induced ulcerative colitis in mice. Macromolecular Bioscience 2024, 2300465. IF=4.6

        6. Da Huang,* Qiang Tang, Minglang Zou, Yongming Wang, Fang Luo, Jinyi Mu, Yuanzi Wu, Zuquan Weng* and Zhenyu Lin. Anti-inflammatory unimolecular micelles of redox-responsive hyperbranched polycurcumin amphiphiles with enhanced anti-inflammatory efficacy in vitro and in vivo. Polymer Chemistry 2023, 14, 5208-5217. IF=5.364

        7. Chenlan Xu, Shuting Chen, Cuiping Chen, Yangcan Ming, Jiahao Du, Jinyi Mu, Fang Luo, Da Huang,* Na Wang,* Zhenyu Lin and Zuquan Weng.* Colon-targeted oral nanoparticles based on ROS-scavenging hydroxyethyl starch-curcumin conjugates for efficient inflammatory bowel disease therapy. International Journal of Pharmaceutics 2022, 623, 121884. IF=6.51

        8. Fang Luo, Yating Zhang, Yexin Zu, Shiqing Li, Yiting Chen, Zhonghui Chen, Da Huang,* Bin Qiu, Zhenyu Lin.* Quick preparation of water-soluble perovskite nanocomposite via cetyltrimethylammonium bromide and its application. Microchimica Acta 2022, 189, 68. IF=6.408

        9. Da Huang, Kristoffer Valerie, Hu Yang.* Clickable biocompatible brush polymers as a versatile platform toward development of multifunctional drug delivery vehicles. Reactive and Functional Polymers 2022, 170, 105147. IF=4.966

        10. Fang Luo, Shiqing Li, Limei Cui, Yexing Zu, Yiting Chen, Da Huang,* Zuquan Weng, Zhenyu Lin.* Biocompatible perovskite quantum dots with superior water resistance enable long-term monitoring of the H2S level in vivo. Nanoscale 2021, 13, 14297-14303. IF=8.307

        11. Shuting Chen, Jie Wu, Qiang Tang, Chenlan Xu, Yan Huang, Da Huang,* Fang Luo, Yuanzi Wu, Fen Yan, Zuquan Weng* and Shaoyun Wang. Nano-micelles based on hydroxyethyl starch-curcumin conjugates for improved stability, antioxidant and anticancer activity of curcumin. Carbohydrate Polymers 2020, 228, 115398. IF=10.723

        12. Jiamin Chen, Yi Lu, Fen Yan, Yuanzi Wu, Da Huang* and Zuquan Weng*. A fluorescent biosensor based on catalytic activity of platinum nanoparticles for freshness evaluation of aquatic products. Food Chemistry 2020, 310, 125922. IF=9.231

        13. Da Huang, Mi Sun, Yazhong Bu, Fang Luo, Cuiying Lin,* Zhenyu Lin, Zuquan Weng, Fei Yang* and Decheng Wu. Microcapsule-embedded hydrogel patches for ultrasound responsive and enhanced transdermal delivery of diclofenac sodium. Journal of Materials Chemistry B 2019, 7, 2330-2337. IF=7.571

        14. Lixu Wang, Chaoqun Chen, Huawei Huang, Da Huang,* Fang Luo, Bin Qiu, Longhua Guo,* Zhenyu Lin and Huanghao Yang. Sensitive detection of telomerase activity in cancer cells using portable pH meter as readout. Biosensors & Bioelectronics 2018, 121, 153-158. IF=12.545

        15. Da Huang, Yaping Zhuang, Fei Yang, Hong Shen, Xing Wang and Decheng Wu.* Acetal-linked PEGylated paclitaxel prodrugs forming free-paclitaxel-loaded pH-responsive micelles with high drug loading capacity and improved drug delivery. Materials Science & Engineering: C 2018, 82, 60-68. IF=8.457

        16. Da Huang and Decheng Wu.* Biodegradable dendrimers for drug delivery. Materials Science & Engineering: C 2018, 90, 713-727. IF=8.457

        17. Da Huang, Yaqiang Wang, Fei Yang, Hong Shen, Zuquan Weng and Decheng Wu.* Charge-reversible and pH-responsive biodegradable micelles and vesicles from linear-dendritic supramolecular amphiphiles for anticancer drug delivery. Polymer Chemistry 2017, 8, 6675-6687. IF=5.364

        18. Da Huang, Fei Yang, Xing Wang, Hong Shen, Yezi You and Decheng Wu.* Facile synthesis and self-assembly behavior of pH-responsive degradable polyacetal dendrimers. Polymer Chemistry 2016, 7, 6154-6158. IF=5.364

        19. Da Huang, Dawei Li, Tiantian Wang, Hong Shen, Pei Zhao, Baoxia Liu, Yezi You, Yuanzheng Ma,* Fei Yang,* Decheng Wu* and Shenguo Wang. Isoniazid conjugated poly(lactide-co-glycolide): long-term controlled drug release and tissue regeneration for bone tuberculosis therapy. Biomaterials 2015, 52, 417-425. IF=15.304

        獲獎情況

        2024.10指導學生獲2024年研究生國家獎學金

        2023.07獲beat365在線體育官網2023屆優秀本科生畢業論文指導教師獎

        2019.10指導學生獲2019年研究生國家獎學金

        其他

        指導研究生多人赴中科院、廈門大學、華南理工大學等知名院校攻讀博士,進一步深造。

        Researchgate個人主頁: https://www.researchgate.net/profile/Da-Huang-5


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